Nelly Cummings scored 13 points and No. 11 seed Pittsburgh held sixth-seeded Iowa State to 23% shooting in a 59-41 victory in the first round of the NCAA Tournament.

Jamarius Burton made a go-ahead jumper with 10 seconds left and Pitt edged Mississippi State 60-59 in a back-and-forth First Four game that featured 21 lead changes — most in the NCAA Tournament in five years.

Pittsburgh finds itself atop the ACC with just two weeks left in the regular season.

Justin Lewis buried a 3 from the top of the arc with 11.5 seconds left to send Marquette to a 57-54 win over No. 11 Villanova.