Kyler Murray scored five touchdowns and linebacker Chandler Jones had a career-high five sacks as the Arizona Cardinals simply dominated the Tennessee Titans 38-13 for a big road win to open the season.

Briean Boddy-Calhoun returned a fumble 42 yards for a touchdown and the Tennessee Titans beat the Super Bowl champion Tampa Bay Buccaneers, who played without Tom Brady and several starters, 34-3.

Cleveland Browns quarterback Baker Mayfield leaves the field after an NFL football game against the New York Jets, Sunday, Dec. 27, 2020, in East Rutherford, N.J. (AP Photo/Bill Kostroun)EAST RUTHERFORD, N.J. – Baker Mayfield coughed up the ball — and the Cleveland Browns' chances to wrap up a playoff spot. After a 23-16 loss to the New York Jets on Sunday, the Browns will need to beat the Pittsburgh Steelers next Sunday if they're going to end the NFL's longest playoff drought. The call was upheld by video review, and the Jets (2-13) sealed their second straight victory after an 0-13 start. Mayfield then marched the Browns downfield, and Nick Chubb's 1-yard run made it 20-10 with 2:56 left in the third quarter.

Coach Adam Gase got his first win of the year only after New York blew most of a 17-point lead in the second half. New York had a 13-3 lead at halftime after holding the Rams to 97 yards, and the Jets led 20-3 midway through the third quarter. Nsimba Webster’s huge punt return put the Rams in Jets territory moments later, but the New York defense held with help from penalties. INJURIESJets: DL Quinnen Williams left in the second half to be evaluated for a head injury. ... WR Jeff Smith injured his shoulder in the second half.

(AP Photo/John Froschauer)Denver Broncos running back Phillip Lindsay has cleared concussion protocol and will play against the Los Angeles Chargers. Bears: WR Ted Ginn Jr., DB Duke Shelley, RB Artavis Pierce, OL Cody Whitehair, WR Riley Ridley, LB Trevis Gipson. Seahawks: RB Chris Carson, RB Carlos Hyde, DE Benson Mayowa, CB Ugo Amadi, SS Jamal Adams, CB Shaquill Griffin. ___LOS ANGELES RAMS AT MIAMIRams: RB Raymond Calais, OL Brian Allen, WR Trishton Jackson, TE Brycen Hopkins, DL A’Shawn Robinson. Dolphins: RB/WR Lynn Bowden Jr., RB Salvon Ahmed, FB Chandler Cox, CB Jamal Perry, RB Jordan Howard, DE Jason Strowbridge.

Titans: CB Joshua Kalu, LB Derick Roberson, LB David Long Jr., OL Daniel Munyer, T Isaiah Wilson, DL Matt Dickerson. Washington: T Geron Christian, WR Isaiah Wright, DE James Smith Williams, WR Robert Foster, LB Thomas Davis, DE Casey Toohill. ___DETROIT AT ATLANTALions: QB David Blough, CB Desmond Trufant, S Miles Killebrew, OL Logan Stenberg, WR Quintez Cephus, RB Bo Scarbrough. ___GREEN BAY AT HOUSTONPackers: QB Jordan Love, CB Kevin King, S Darnell Savage, RB Tyler Ervin, RB Aaron Jones, T David Bakhtiari, DL Tyler Lancaster. Texans: WR Keke Coutee, CB John Reid, LB Peter Kalambayi, T Charlie Heck, TE Jordan Akins.

The Jets (0-6) became the NFL's only winless team and continued their worst start since 1996, increasing the heat on embattled coach Adam Gase. The Dolphins blanked the Jets for the first time since the January 1983 AFC championship game, which they won 14-0. The two teams were a combined 0 for 19 on third downs before the Jets finally converted with 11 minutes left. The Dolphins' only third-down conversion came on a completion by Tagovailoa, who went 2 for 2 for 9 yards. ANTHEMRunning back Ty Jackson was the only player kneeling for the Jets during “The Star-Spangled Banner.”The Dolphins stayed in the locker room.

On third-and-6 and the Jets leading by one, Quinnen Williams sacked Brett Rypien — but grabbed the quarterback’s helmet and prolonged the drive. Brian Poole then intercepted Rypien, making his first NFL start, on the Broncos’ next possession, giving the Jets the ball at Denver’s 44. Darnold gave the Jets their first lead of the season with a dazzling run that would make running back teammates Frank Gore and Le'Veon Bell proud. Darnold was able to come back early in the second quarter on the Jets' next series — and was promptly sacked again. The Jets took advantage — eventually.

Still, short-handed San Francisco had enough to beat the inept New York Jets. Defensive end Nick Bosa and defensive tackle Solomon Thomas were both carted off the field two plays apart with left knee injuries in the first quarter. Two plays later, Thomas was carted off — also with a left knee injury — after an 8-yard reception by Chris Hogan. San Francisco ended the 14-play possession with an 18-yard catch by Jordan Reed for the first of his two TD grabs. ... San Francisco wide receiver Brandon Aiyuk, a first-round draft pick, had two catches for 21 yards in his NFL debut.

NEW YORK – The New York Jets were looking at fourth-and-really long - and another brutal loss to the Miami Dolphins. “I thought it was pass interference," Darnold said. But, the Jets argued Nik Needham interfered with the receiver by wrapping his right arm around Smith's right shoulder. “I knew it was pass interference from the beginning," Smith said. Two plays later, Ficken won it, helping the Jets (5-8) avoid a season series sweep by the lowly Dolphins (3-10).