There's a new traffic pattern on State Road 46, from French Avenue (U.S. 17-92) to Mellonville Avenue.

An 82-year-old Brevard County woman died in a head-on crash after briefly going the wrong way, the Florida Highway Patrol said.

If you’ve ever sat in traffic on Interstate 4 during rush hour in Seminole County, maybe you’ve seen how some drivers take the exit ramp down to State Road 46 and then illegally cross the road to get back onto I-4 eastbound.

The family of a man who was murdered at a Seminole County apartment complex nearly two years ago hopes telling his story will make a difference.

The Mount Dora City Council postponed a vote over whether to move forward with a controversial development in the Wolf Branch Innovation District.

Troopers said the crash happened around 6:56 p.m. at State Road 46 and Richmond Avenue.

A motorcyclist from Merritt Island was killed in a series of crashes involving five vehicles Saturday night on Interstate 95 in the Mims area.

In a release, troopers said that the crash happened around 1:22 p.m. along State Road 46 east of Pitbull Lane in Mims.

An overturned dump truck has Monroe Road temporarily closed Wednesday afternoon, according to the Seminole County Fire Department.

A fatal crash in Sorrento has shut down State Road 46 in both directions.

A Sanford police officer was arrested Sunday morning, accused of driving under the influence along State Road 46.

A 36-year-old Apopka man was struck and killed Friday night while riding a bicycle along State Road 46 in Lake County, according to the Florida Highway Patrol.

Sanford police are searching for the suspect vehicle in a hit-and-run crash that left a man critically injured earlier this week.

The Florida Department of Transportation announced lane closures along State Road 429 on Thursday due to an "interagency coordination."

A man was killed after being hit by a truck and going into a ditch in a Brevard County crash Friday morning, according to the Florida Highway Patrol.

Mount Dora leaders are set to take a final vote on the development of a new district off State Road 46 that has received pushback from residents.

A 23-year-old man died after losing control of his pickup truck and crashing into a fence and bridge support on State Road 46 in Lake County, according to Florida Highway Patrol.

A pedestrian was killed in a crash Tuesday evening on State Road 46 in Sanford, according to the Sanford Police Department.

Jason Reichman said his restaurant is still underwater two weeks after Hurricane Ian.

The Florida Department of Transportation announced an emergency road closure of all lanes of State Road 46 at the St. Johns River in Brevard County.

A smoking car forced the closure of State Road 46 in Seminole County, according to fire officials.

Florida Forest Service officials responded to a wildfire which closed State Road 46 near at Seminole Ranch Conservation Area for hours Monday afternoon.

The children were traveling with a 20-year-old male driver, a 21-year-old female passenger and a 1-year-old boy in a 2011 KIA when the car started passing traffic in a no passing zone, troopers said.

A crash shut down a part of State Road 46 in Sanford Friday night, according to police.

A father and son pair from Eustis died Friday in a fiery wreck on State Road 46, the Florida Highway Patrol said.

Two Seminole County roads are closed in both directions after a truck carrying treated human waste had an accident Friday afternoon, fire officials said.

A fatal crash is investigated by the FHP in Lake County.

Troopers are searching for a driver of a red sedan, possibly a Hyundai, after a double fatal crash around 6:10 p.m. Thursday in the area of State Road 46 and Wekiva Pines Boulevard in Lake County, according to the Florida Highway Patrol.

A multi-vehicle crash has State Road 46 in Mims shut down Sunday afternoon, according to the Brevard County Fire Rescue.

SEMINOLE COUNTY, Fla. – A fatal crash is under investigation Thursday after the driver of a Dodge Charger crashed into a wall near I-4 in Seminole County, the Florida Highway Patrol said. The wreck was reported on the exit ramp from I-4 east to the State Road 46 exit ramp. According to the FHP crash report, the 51-year-old driver of a Dodge Charger drove onto the exit ramp, left the roadway and ran into the wall supporting the overpass. The driver was pronounced dead at the scene of the crash. The crash remains under investigation.

SEMINOLE COUNTY, Fla. Seminole County Fire Department hazmat teams responded to a gas leak Tuesday morning on State Road 46. The leak was contained by the hazmat crew but westbound SR 46 was closed around 10 a.m. from Elder Road to Rinehart Road. No other information was provided. Check back for updates.