Zach Wilson threw a touchdown pass and ran for another and the short-handed New York Jets used a goal-line stand at the end of the game to beat Trevor Lawrence and the Jacksonville Jaguars 26-21.

Reigning Defensive Rookie of the Year Chase Young suffered a potentially serious right knee injury, putting a damper on Washington’s big win against Tom Brady and the Tampa Bay Buccaneers.

Jonathan Taylor rushed for 116 yards and a touchdown, Indianapolis returned a blocked punt for a score and the Colts’ defense held on for a 23-17 victory over the Jacksonville Jaguars.

Jacksonville’s losing streak is far from a fluke.

Joe Burrow of the Cincinnati Bengals was taken to a hospital as a precaution after suffering a bruised throat and Daniel Jones of the New York Giants was carted off the field with a concussion on a rough day for young quarterbacks.

Derrick Henry ran for 130 yards and three touchdowns, Kevin Byard returned a fumble for a score and the Tennessee Titans beat Jacksonville 37-19, sending the Jaguars to their 20th consecutive loss.

Taylor's breakout game, given the circumstances, will never be forgotten by Colts fans. The Jags lost their final 15 games after beating the Colts in the season opener. Colts: Jared Veldheer started in place of injured LT Anthony Castonzo, and the Colts were without two starters in the secondary — S Khari Willis and CB Rock Ya-Sin. Colts: Rivers' TD pass, No. Hilton caught his 50th career TD pass, tying the late Jimmy Orr for fourth on the franchise list.

(AP Photo/Aaron Doster)The New York Giants will be without starting quarterback Daniel Jones for Sunday’s game against the Seattle Seahawks. Jones was not expected to play because of a hamstring injury suffered last week against Cincinnati. Colt McCoy will make his first start of the season at QB for the Giants. Seattle was without both starting right tackle Brandon Shell (ankle) and backup Cedric Ogbuehi (calf) leaving a major question on the offensive line. ___CLEVELAND-TENNESSEEBrowns: WR Taywan Taylor, WR KhaDarel Hodge, CB Denzel Ward, RB Dontrell Hilliard, S Tedric Thompson, DE Joe Jackson.

The unbeaten Pittsburgh Steelers wound up relatively healthy for their game against the AFC North rival Cincinnati Bengals following a brush with the novel coronavirus. Defensive tackle Tyson Alualu is also back after missing a game with a knee injury. Cincinnati is without running back Joe Mixon, whose lingering foot injury is forcing him to miss a third game in a row. Receiver Cooper Kupp, left tackle Andrew Whitworth and running back Darrell Henderson all were active after missing practices with injuries. Raiders: T Kolton Miller (ankle), DT Maurice Hurst (ankle), QB Marcus Mariota, RB Theo Riddick, G John Simpson, DT Daniel Ross.

Los Angeles Chargers quarterback Justin Herbert (10) celebrates his rushing touchdown with Joshua Kelley (27) during the second half of an NFL football game against the Jacksonville Jaguars Sunday, Oct. 25, 2020, in Inglewood, Calif. (AP Photo/Kyusung Gong)INGLEWOOD, Calif. – At last, a victory. The rookie threw for a season-high 347 yards and three touchdowns as well as running for a score as the Chargers defeated the Jacksonville Jaguars 39-29 to snap a four-game losing streak. James Robinson led the Jaguars with 119 rushing yards on 22 carries and scored two touchdowns (one rushing, one receiving). After Badgley's 35-yard field goal on the opening drive, rookie Joe Reed scored his first NFL touchdown on a 7-yard jet sweep around right end. It was the Chargers' first rushing touchdown since Herbert in Week 2 against Kansas City.

Jones had been listed as questionable after missing practice throughout the week with a hamstring injury. Even so, the winless Falcons’ secondary gets a boost with safeties Keanu Neal (hamstring) and Ricardo Allen (elbow) returning from injuries. ___PHILADELPHIA AT PITTSBURGHEagles: TE Hakeem Butler; RB Jason Huntley, WR DeSean Jackson, WR Alshon Jeffery, CB Avonte Maddox, QB Nate Sudfeld, DE Casey Toohill. Falcons: S Jaylinn Hawkins, WR Julio Jones, CB A.J. Ravens: RB Justice Hill, WR Chris Moore, QB Trace McSorley, DT Broderick Washington, DT Justin Ellis, OL Tyre Phillips.